John D. Gearhart (decd. 2020) was the James W. Effron University Professor, Professor of Cell and Developmental Biology, and Professor of Biological Sciences, with appointments in the Perelman School of Medicine and the School of Veterinary Medicine from July 1, 2008 until his death in May 2020. Gearhart worked at the intersection of developmental biology, genetics and therapeutics.
REASEARCH INTERESTS (selected)
- Stem Cells
- Regenerative Medicine
ACADEMIC WRITINGS (SELECTED)
"Human Pluripotent Stem Cell Research: Past, Present, and Future," Cell Research, August 4, 2008
"Optimal isolation and xeno-free culture conditions for limbal stem cell function," Invest Ophthalmol Vis Sci, Jan 20, 2014
"The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2),"
J Biol Chem, June 2013
"Optimization of direct fibroblast reprogramming to cardiomyocytes using calcium activity as a functional measure of success," J Mol Cell Cardiol. 2013
For a full list, visit Gearhart's Perelman School of Medicine faculty page.
INTERVIEWS, FEATURES, AND ANNOUNCEMENTS (SELECTED)
"Pushing the Boundaries of Science to Advance Human Health," Wharton Business Radio, December 23, 2015 (with Jonathan Moreno)
"Symposium on Cellular Reprogramming to be Held at Penn Medicine," Penn Medicine, Press Release, April 8, 2014
"Talking About Regeneration," Philadelphia Business Journal (pg 2), March 21, 2014
"John Gearhart, Stem Cell Pioneer, Named Penn's Institute for Regenerative Medicine Director and PIK Professor," Penn News, July 23, 2008
"Generating A Home for Regenerative Medicine," Penn Medicine, Spring 2009
"A Decade of Stem-Cell Research. An Interview with John Gearhart," Embo Reports, December 2008
"Pondering the Ethics and Science of Stem Cells," Penn Gazetteer, 2002
"Stem Cell Pioneer," Penn Current, September 4, 2008
"John Gearhart, Stem Cell Pioneer, Named Penn's Institute for Regenerative Medicine Director and PIK Professor," Penn Medicine, Press Release, July 28, 2008
"Instructing Our Own Cells To Rebuild Our Bodies," Engaging Minds, University of Pennsylvania Speaker Series, 2010